Engineered bacteria are turned into cancer fighters

Salmonella

Immunotherapic agents are of many kinds: antibodies, vaccines, cytokines and even…bacteria. The immune system has more difficulty in recognizing cancer cells than any foreign invaders. A tumour is made of the host’s own cells, only more selfish, rebellious and disobedient. On the contrary, bacteria are completely different due to their peculiar cellular structures and metabolic functions: the body’s own defences are much more prepared to identify and attack them. Can we turn bacteria into cancer fighters that help the immune system to destroy cancer cells?

Veterinary Immunotherapy and Translational Research

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